![]() WePay, which is also owned by Chase, reportedly failed to provide ticket services for the Defense of Liberty organization, a conservative group, in 2021 because the event was showcasing Donald Trump Jr., the former president's son. In addition, there have been at least two other instances where Chase 'has not extended its openness and inclusivity to everyone,' the state AGs say.įamily Council, a pro-life group, had its account terminated from a credit card processor owned by Chase in 2021 after it was considered 'High Risk' by the company. Worse, it flies in the face of basic American values of fairness and equality,' the attorneys general say in the letter to Dimon. 'The bank's brazen attempt to condition critical services on a customer passing some unarticulated religious or political litmus test flies in the face of Chase's anti- discrimination policies. ![]() ![]() Ambassador-at-Large for International Religious Freedom Sam Brownback, is a known 'multi-faith' nonprofit.Ī deal was announced earlier on Monday that allows for an orderly failure of First Republic, following the announcement that JPMorgan Chase purchased the bankīrownback said in October that he was 'stunned' that the bank had closed NCRF's checking account and wouldn't provide a sufficient answer as to the reasons behind the closure.Īccording to the letter, eventually a Chase employee contacted NCRF saying the bank would restore the account, but only if the organization provided a list of their donors, a list of political candidates it intended to support and reasoning behind the endorsements. NCRF, which was founded by the former U.S. The attorneys general point to Chase's alleged 'de-banking' of a religious liberty organization last year - the National Committee for Religious Freedom (NCRF) - with no clear explanation. In a letter to JPMorgan Chase CEO Jamie Dimon Tuesday, the state attorneys general led by Daniel Cameron of Kentucky allege the company has 'persistently discriminated' against customers due to 'religious or political affiliation.'Ĭhase claims that it opposes 'discrimination in any form,' yet the GOP state leaders allege it has repeatedly targeted religious liberty organizations by shutting down their checking accounts and refusing them other key banking services because of their political leanings, a practice now known as 'de-banking.' These findings suggest that HSF1 is important in the ovarian cancer TGFβ response and in EMT.A group of 19 GOP state attorneys general are putting JPMorgan Chase on notice for alleged discrimination against religious and other conservative organizations, which contradicts the company's commitment to 'inclusivity,' they say. In the spheroid model, cells more readily undergo EMT however, EMT inhibition by HSF1 becomes more pronounced in the spheroid model. To further explore the role of HSF1 in ovarian cancer EMT, we cultured multicellular spheroids in a non-adherent environment to simulate early avascular tumors. Knockdown of HSF1 in SKOV3 and HEY ovarian cancer cell lines attenuates the epithelial-to-mesenchymal transition (EMT) in cells treated with TGFβ, as determined by western blot and quantitative RT-PCR analysis of multiple EMT markers. In order to determine the role of HSF1 in ovarian cancer, inducible HSF1 knockdown cell lines were created. Upon analysis of various patient data sets, we find that HSF1 is frequently overexpressed in ovarian tumor samples. ![]() The proteotoxic stress-responsive transcription factor HSF1 is frequently overexpressed in a variety of cancers and is vital to cellular proliferation and invasion in some cancers. Ovarian cancer is the most lethal gynecological cancer, with over 200,000 women diagnosed each year and over half of those cases leading to death.
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